ALACHUA, FL, USA I August 26, 2015 and OSAKA, Japan I August 27, 2015 I Takeda Pharmaceutical Company Limited (Takeda) and Nanotherapeutics, Inc., announced an agreement providing Takeda with expanded commercialization and technology access rights related to Nanotherapeutics’ Vero cell technology platform – a cell culture-based platform for vaccine production which Nanotherapeutics acquired from Baxalta, formerly Baxter International’s BioScience division. Financial terms of the agreement were not disclosed.

In 2010, Takeda and Baxter entered into an agreement in which Takeda licensed from Baxter certain exclusive rights to the technology for the development of pandemic and seasonal influenza vaccines for the Japanese market. Takeda’s cell culture-based H5N1 and prototype vaccine for pandemic influenza was developed on this platform and was approved in Japan in March 2014. Takeda is currently developing a cell-based seasonal flu vaccine (TAK-850) on the same platform for use in Japan.

The agreement with Nanotherapeutics extinguishes Takeda’s remaining financial obligations under the initial agreement with Baxter. Additionally, Takeda gains rights to commercialize its pandemic and seasonal influenza vaccine products, based on the Vero cell technology platform, in certain regions outside of Japan and will have access to Vero cell technology and reagents for the development of vaccines beyond influenza.

“We are delighted to partner with Nanotherapeutics to create the opportunity to expand the reach of Takeda’s pandemic and seasonal flu vaccines to other parts of the world,” said Rajeev Venkayya, M.D., President of Takeda’s Vaccine Business Unit. “Today’s agreement reinforces Takeda’s commitment to its global vaccine business and our goal of reaching as many people as possible with vaccines that address important unmet needs in global public health.”

James Talton, Ph.D., President and Chief Executive Officer of Nanotherapeutics, noted, “Our acquisition of the Vero cell technology has meaningfully strengthened and increased our core capabilities and internal product portfolio. That said, we are very pleased to be able to partner with global pharmaceutical leader, Takeda, to expand their access to the technology for further expansion of their vaccine pipeline, thereby also allowing Nanotherapeutics to align itself with a company which has approved and late-stage products in development based on this proven technology platform.”

About Nanotherapeutics

Nanotherapeutics, based in Alachua, FL, is an integrated biopharmaceutical company with a focus on development and manufacturing. The Company has expertise in preclinical and clinical development, formulation optimization, and cGMP manufacturing of biopharmaceutical products and medical devices. The Company’s proprietary platform technologies can be used with all drug types, ranging from small molecules to proteins and vaccines. For more information, visit the Company website at

About Vero cell technology

On December 9 2014, Baxter International Inc. announced that it has entered into a definitive agreement to sell its proprietary Vero cell technology and related assets, including its production facility in Bohumil, Czech Republic, to Nanotherapeutics, Inc. The Vero cell platform is an advanced, cell-based technology for vaccine production. The agreement with Nanotherapeutics includes all assets related to the platform, including vaccines for H5N1, H1N1 and seasonal influenza. The agreement also includes investigational vaccine programs for Ross River virus, Chikungunya disease and West Nile virus.

About Takeda Pharmaceutical Company Limited

Located in Osaka, Japan, Takeda (TSE: 4502) is a research-based global company with its main focus on pharmaceuticals. As the largest pharmaceutical company in Japan and one of the global leaders of the industry, Takeda is committed to strive towards better health for people worldwide through leading innovation in medicine.

Additional information about Takeda is available through its corporate website,

About Takeda’s Vaccine Business Unit

Takeda has supplied vaccines to protect the health of people in Japan for more than 60 years. Launched in 2012 and headquartered in Deerfield, Illinois, Takeda’s global Vaccine Business is tackling some of the world’s most challenging infectious diseases for which vaccines do not exist, such as dengue and norovirus.

SOURCE: Takeda Pharmaceutical Co