BEVERLY HILLS, CA, USA I December 28, 2015 I Rich Pharmaceuticals, Inc. (OTC Markets: RCHA) (“Rich Pharmaceuticals” or the “Company”) is pleased to announce that the Company has received approval from the U.S. Food and Drug Administration (FDA) to commence its Phase 1/2 clinical for the treatment of Acute Myelocytic Leukemia (AML) and Myelodysplastic Syndrome (MDS) patients. The FDA has approved the Company’s Investigational New Drug (IND) application and has approved the Company’s commencement of a clinical program titled “A Phase 1/2, Evaluation of the Safety and Efficacy of RP-323 in Combination with all-trans-Retinoic Acid, Sodium Butyrate, and 1α, 25-dihydroxyvitamin D3 in Subjects with Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)”. This approval gives the Company an immediate go ahead to start patient enrollment for a Phase 1/2 study using Rich Pharmaceuticals’ lead compound RP-323 in clinical trials.
“This is a very exciting time at Rich Pharmaceuticals. I am pleased to announce that we have reached our most significant milestone to date,” said Chief Executive Officer, Ben Chang. “Our team is enthusiastic with this development and we look forward to considerable advancement as we plan to begin clinical trials in the upcoming year.”
About Rich Pharmaceuticals:
Rich Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies in oncology, with initial concentration in treating AML, Hodgkin’s Lymphoma and other blood related diseases. Rich Pharmaceuticals’ goal is to extend refractory patients life expectancy and increase quality of life. Rich Pharmaceuticals’ primary development stage product candidate, RP-323, is being designed to treat blood and cancer related diseases through non-evasive outpatient facilities. RP-323 is a phorbol ester, which induces differentiation and/or apoptosis in multiple cell lines and primary cells, activates protein kinase C (PKC), and modulates the activity of multiple downstream cell signaling pathways, including mitogen-activated protein kinase (MAPK) pathways. RP-323 induces PKC to produce NF kappa, which then produces NF kappa B that has the ability to regulate cellular responses by entering into the nucleus of cells. NF kappa B binds to DNA and changes the nature of the cell and (1) induces differentiation; (2) induces proliferation; (3) cytokine induction; (4) and/or apoptosis. Find out more at www.richpharmaceuticals.com
Acute Myelocytic Leukemia (AML), also known as Acute Myelogenous Leukemia, is the most common acute leukemia type that affects mostly adults. AML is an aggressive form of cancer of the blood and the bone marrow, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal white blood cells. In the U.S., over 20,000 new cases of AML are diagnosed annually.
Myelodysplastic Syndrome (MDS) occurs when the blood-forming cells in the bone marrow are damaged which leads to low numbers of one or more types of blood cells. In MDS, some of the cells in the bone marrow are damaged and have problems making new blood cells. Many of the blood cells that are made by these damaged cells are not normal. The abnormal blood cells die sooner than normal cells, leaving the person without enough normal blood cells and with low blood counts. MDS can turn into a fast-growing cancer of bone marrow cells called acute myelocytic leukemia and occurs in about 1 out of 3 people with MDS.
SOURCE: Rich Pharmaceuticals
Post Views: 19
BEVERLY HILLS, CA, USA I December 28, 2015 I Rich Pharmaceuticals, Inc. (OTC Markets: RCHA) (“Rich Pharmaceuticals” or the “Company”) is pleased to announce that the Company has received approval from the U.S. Food and Drug Administration (FDA) to commence its Phase 1/2 clinical for the treatment of Acute Myelocytic Leukemia (AML) and Myelodysplastic Syndrome (MDS) patients. The FDA has approved the Company’s Investigational New Drug (IND) application and has approved the Company’s commencement of a clinical program titled “A Phase 1/2, Evaluation of the Safety and Efficacy of RP-323 in Combination with all-trans-Retinoic Acid, Sodium Butyrate, and 1α, 25-dihydroxyvitamin D3 in Subjects with Relapsed or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)”. This approval gives the Company an immediate go ahead to start patient enrollment for a Phase 1/2 study using Rich Pharmaceuticals’ lead compound RP-323 in clinical trials.
“This is a very exciting time at Rich Pharmaceuticals. I am pleased to announce that we have reached our most significant milestone to date,” said Chief Executive Officer, Ben Chang. “Our team is enthusiastic with this development and we look forward to considerable advancement as we plan to begin clinical trials in the upcoming year.”
About Rich Pharmaceuticals:
Rich Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies in oncology, with initial concentration in treating AML, Hodgkin’s Lymphoma and other blood related diseases. Rich Pharmaceuticals’ goal is to extend refractory patients life expectancy and increase quality of life. Rich Pharmaceuticals’ primary development stage product candidate, RP-323, is being designed to treat blood and cancer related diseases through non-evasive outpatient facilities. RP-323 is a phorbol ester, which induces differentiation and/or apoptosis in multiple cell lines and primary cells, activates protein kinase C (PKC), and modulates the activity of multiple downstream cell signaling pathways, including mitogen-activated protein kinase (MAPK) pathways. RP-323 induces PKC to produce NF kappa, which then produces NF kappa B that has the ability to regulate cellular responses by entering into the nucleus of cells. NF kappa B binds to DNA and changes the nature of the cell and (1) induces differentiation; (2) induces proliferation; (3) cytokine induction; (4) and/or apoptosis. Find out more at www.richpharmaceuticals.com
Acute Myelocytic Leukemia (AML), also known as Acute Myelogenous Leukemia, is the most common acute leukemia type that affects mostly adults. AML is an aggressive form of cancer of the blood and the bone marrow, characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal white blood cells. In the U.S., over 20,000 new cases of AML are diagnosed annually.
Myelodysplastic Syndrome (MDS) occurs when the blood-forming cells in the bone marrow are damaged which leads to low numbers of one or more types of blood cells. In MDS, some of the cells in the bone marrow are damaged and have problems making new blood cells. Many of the blood cells that are made by these damaged cells are not normal. The abnormal blood cells die sooner than normal cells, leaving the person without enough normal blood cells and with low blood counts. MDS can turn into a fast-growing cancer of bone marrow cells called acute myelocytic leukemia and occurs in about 1 out of 3 people with MDS.
SOURCE: Rich Pharmaceuticals
Post Views: 19
