Supported by a $275 million private investment, the merger is expected to create a combined entity focused on advancing Oruka’s portfolio of novel biologics that aim to redefine the standard of care for patients with chronic skin diseases
Founding CEO Lawrence Klein, Ph.D., brings deep industry experience to advance Oruka’s mission of providing patients freedom from disease
The debut of the third company founded based on assets generated by Paragon reaffirms its commitment to rapidly discovering and developing novel therapeutics for patients
WALTHAM, MA, USA I April 3, 2024 I Paragon Therapeutics (“Paragon”), a biotechnology company dedicated to developing best-in-class biologics for a range of diseases with high unmet need, announced today that the third company founded based on assets generated by Paragon, Oruka Therapeutics (“Oruka”), has entered into a definitive agreement with ARCA biopharma to combine the companies in an all-stock transaction. In support of the merger, Oruka has secured commitments for a $275 million private investment from a syndicate of healthcare investors.
“Launching Oruka with such strong investor support is a testament to the company’s differentiated portfolio, experienced leadership team, and focused strategy to transform the treatment paradigm across multiple chronic skin diseases,” said Evan Thompson, Ph.D., Chief Operating Officer of Paragon. “The debut of Oruka reaffirms our commitment to bringing potentially best-in-class therapies to patients as quickly and effectively as possible.”
Founded based on assets generated by Paragon, Oruka emerged in 2024 with a focus on transforming the treatment of plaque psoriasis, psoriatic arthritis, and other dermatologic and inflammatory indications with potentially best-in-class biologics. The combined company, which plans to operate under the name Oruka Therapeutics, Inc., will continue this vision and anticipates rapid advancement of Oruka’s pipeline of potentially best-in-class biologics, with co-lead programs, ORKA-001 and ORKA-002, expected to enter clinical trials in 2025.
“Paragon is truly a world-class team, and their exceptional work has begun to show its potential in the clinic. We are thrilled to have access to development candidates engineered at Paragon that could advance the standard of care in several important indications,” said Lawrence Klein, Ph.D., Chief Executive Officer of Oruka. “At Oruka, we envision a future that offers more patients freedom from chronic skin disease, and we are committed to building this future by developing potentially best-in-class biologics that could offer higher rates of complete disease clearance with as few as one or two doses a year.”
About Oruka Therapeutics
Oruka Therapeutics is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka’s mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as one or twice a year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com.
About Paragon Therapeutics
Paragon Therapeutics, Inc. is a biotechnology company leveraging cutting-edge science and technology to identify and propel best-in-class biologics into the clinic for a range of human diseases with high unmet needs. The company rapidly advances therapies through a range of opportunities, from new company creation and strategic partnerships to shaping programs in-house. Founded by Fairmount in 2021 as a joint venture with FairJourney Biologics, Paragon Therapeutics is based in Waltham, Mass. For more information, please visit www.paragontherapeutics.com.
About Fairmount
Fairmount Funds Management LLC is a Philadelphia-based investment firm dedicated to investing in promising new therapies pursued by biotechnology and life science companies.
SOURCE: Paragon Therapeutics
Post Views: 644
Supported by a $275 million private investment, the merger is expected to create a combined entity focused on advancing Oruka’s portfolio of novel biologics that aim to redefine the standard of care for patients with chronic skin diseases
Founding CEO Lawrence Klein, Ph.D., brings deep industry experience to advance Oruka’s mission of providing patients freedom from disease
The debut of the third company founded based on assets generated by Paragon reaffirms its commitment to rapidly discovering and developing novel therapeutics for patients
WALTHAM, MA, USA I April 3, 2024 I Paragon Therapeutics (“Paragon”), a biotechnology company dedicated to developing best-in-class biologics for a range of diseases with high unmet need, announced today that the third company founded based on assets generated by Paragon, Oruka Therapeutics (“Oruka”), has entered into a definitive agreement with ARCA biopharma to combine the companies in an all-stock transaction. In support of the merger, Oruka has secured commitments for a $275 million private investment from a syndicate of healthcare investors.
“Launching Oruka with such strong investor support is a testament to the company’s differentiated portfolio, experienced leadership team, and focused strategy to transform the treatment paradigm across multiple chronic skin diseases,” said Evan Thompson, Ph.D., Chief Operating Officer of Paragon. “The debut of Oruka reaffirms our commitment to bringing potentially best-in-class therapies to patients as quickly and effectively as possible.”
Founded based on assets generated by Paragon, Oruka emerged in 2024 with a focus on transforming the treatment of plaque psoriasis, psoriatic arthritis, and other dermatologic and inflammatory indications with potentially best-in-class biologics. The combined company, which plans to operate under the name Oruka Therapeutics, Inc., will continue this vision and anticipates rapid advancement of Oruka’s pipeline of potentially best-in-class biologics, with co-lead programs, ORKA-001 and ORKA-002, expected to enter clinical trials in 2025.
“Paragon is truly a world-class team, and their exceptional work has begun to show its potential in the clinic. We are thrilled to have access to development candidates engineered at Paragon that could advance the standard of care in several important indications,” said Lawrence Klein, Ph.D., Chief Executive Officer of Oruka. “At Oruka, we envision a future that offers more patients freedom from chronic skin disease, and we are committed to building this future by developing potentially best-in-class biologics that could offer higher rates of complete disease clearance with as few as one or two doses a year.”
About Oruka Therapeutics
Oruka Therapeutics is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Oruka’s mission is to offer patients suffering from chronic skin diseases like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as one or twice a year. Oruka is advancing a proprietary portfolio of potentially best-in-class antibodies that were engineered by Paragon Therapeutics and target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. For more information, visit www.orukatx.com.
About Paragon Therapeutics
Paragon Therapeutics, Inc. is a biotechnology company leveraging cutting-edge science and technology to identify and propel best-in-class biologics into the clinic for a range of human diseases with high unmet needs. The company rapidly advances therapies through a range of opportunities, from new company creation and strategic partnerships to shaping programs in-house. Founded by Fairmount in 2021 as a joint venture with FairJourney Biologics, Paragon Therapeutics is based in Waltham, Mass. For more information, please visit www.paragontherapeutics.com.
About Fairmount
Fairmount Funds Management LLC is a Philadelphia-based investment firm dedicated to investing in promising new therapies pursued by biotechnology and life science companies.
SOURCE: Paragon Therapeutics
Post Views: 644
