STUTTGART, Germany I September 04, 2024 I La Merie Publishing released its newest report with a landscape description and analysis of degrader-antibody conjugate (DAC) stakeholders, platform technologies, development and discovery pipelines and partnering deals from an industry perspective as of September 2024:
Degrader-Antibody Conjugates 2024: A Landscape Analysis of Stakeholders, Technologies, Pipeline and Partnering from an Industry Perspective
The emerging novel drug modality of degrader-antibody conjugates represents the convergence of the existing technologies of antibody-drug conjugation and targeted protein degradation with the goal of combining the strengths and avoiding the limitations of both technologies. DACs combine the specificity of antibodies with the efficiency of degraders of difficult-to-drug protein targets. Degrader-antibody conjugates provide plenty of opportunities for ADC companies to use a novel payload to improve efficacy and the therapeutic window and for targeted protein degradation (TPD) companies to improve cell-specificity, half-life and drug-like properties.
The report brings you up-to-date with information about and analysis of:
- Stakeholders in the field, by company profiles of DAC activities at pharmaceutical and TPD technology companies;
- DAC technologies using PROTAC and molecular glue for proteasomal degradation for intracellular TPD;
- Proteins-of-interest for intracellular degradation;
- E3 ligases used for intracellular degradation;
- DAC technologies using broadly acting degraders for extracellular TPD; and
- DAC technologies with lysosomal pathway degraders;
- Clinical and non-clinical development pipeline of DACs;
- Profiles of clinical stage DACs;
- DAC discovery pipeline;
- Preclinical proof-of-concept of DAC conjugate technologies and constructs;
- Partnering activities (acquisition, licensing, collaborations)
The report “Degrader-Antibody Conjugates 2024: A Landscape Analysis of Stakeholders, Technologies, Pipeline and Partnering from an Industry Perspective” can be acquired at La Merie Publishing’s online store: https://lamerie.com/report/degrader-antibody-conjugates-2024-a-landscape-analysis-of-stakeholders-technologies-pipeline-and-partnering-from-an-industry-perspective/
About La Merie Publishing
La Merie Publishing is an independent business information provider for the biotechnology and pharmaceutical industry. La Merie Publishing prepares brief and full reports. La Merie Publishing products can be purchased in the online store www.lamerie.com and from selected Resellers.
La Merie Publishing offers the service of custom report preparation for corporate clients, including, but not limited to, pipeline analysis reports, drug profiles and any other competitive intelligence elaboration of interest.
SOURCE: La Merie Publishing
Post Views: 2,061
STUTTGART, Germany I September 04, 2024 I La Merie Publishing released its newest report with a landscape description and analysis of degrader-antibody conjugate (DAC) stakeholders, platform technologies, development and discovery pipelines and partnering deals from an industry perspective as of September 2024:
Degrader-Antibody Conjugates 2024: A Landscape Analysis of Stakeholders, Technologies, Pipeline and Partnering from an Industry Perspective
The emerging novel drug modality of degrader-antibody conjugates represents the convergence of the existing technologies of antibody-drug conjugation and targeted protein degradation with the goal of combining the strengths and avoiding the limitations of both technologies. DACs combine the specificity of antibodies with the efficiency of degraders of difficult-to-drug protein targets. Degrader-antibody conjugates provide plenty of opportunities for ADC companies to use a novel payload to improve efficacy and the therapeutic window and for targeted protein degradation (TPD) companies to improve cell-specificity, half-life and drug-like properties.
The report brings you up-to-date with information about and analysis of:
- Stakeholders in the field, by company profiles of DAC activities at pharmaceutical and TPD technology companies;
- DAC technologies using PROTAC and molecular glue for proteasomal degradation for intracellular TPD;
- Proteins-of-interest for intracellular degradation;
- E3 ligases used for intracellular degradation;
- DAC technologies using broadly acting degraders for extracellular TPD; and
- DAC technologies with lysosomal pathway degraders;
- Clinical and non-clinical development pipeline of DACs;
- Profiles of clinical stage DACs;
- DAC discovery pipeline;
- Preclinical proof-of-concept of DAC conjugate technologies and constructs;
- Partnering activities (acquisition, licensing, collaborations)
The report “Degrader-Antibody Conjugates 2024: A Landscape Analysis of Stakeholders, Technologies, Pipeline and Partnering from an Industry Perspective” can be acquired at La Merie Publishing’s online store: https://lamerie.com/report/degrader-antibody-conjugates-2024-a-landscape-analysis-of-stakeholders-technologies-pipeline-and-partnering-from-an-industry-perspective/
About La Merie Publishing
La Merie Publishing is an independent business information provider for the biotechnology and pharmaceutical industry. La Merie Publishing prepares brief and full reports. La Merie Publishing products can be purchased in the online store www.lamerie.com and from selected Resellers.
La Merie Publishing offers the service of custom report preparation for corporate clients, including, but not limited to, pipeline analysis reports, drug profiles and any other competitive intelligence elaboration of interest.
SOURCE: La Merie Publishing
Post Views: 2,061
