LEBANON, NH, USA I February 2, 2016 I ImmuNext announced today that the first patient has been dosed in a Phase 1 clinical trial of the anti-VISTA antibody, JNJ-61610588. JNJ-61610588 is the first anti-VISTA antibody to enter the clinic.

The compound is a monoclonal antibody designed for the treatment of cancer, and was developed as part of the license and collaboration agreement with Janssen Biotech, Inc.. Janssen Research & Development is running the study.

The Phase I trial will enroll patients with advanced solid tumors. The initial portion of the study is designed to evaluate safety, pharmacokinetics, and pharmacodynamics of ascending doses of JNJ-61610588.

Additional information may be found at clinicaltrials.gov, using identifier NCT02671955.

About ImmuNext

ImmuNext discovers and develops immunomodulatory therapeutics for the treatment of cancer and autoimmune diseases.

The anti-VISTA antibody, JNJ-61610588 is our lead product.   A great team and a great collaboration allowed JNJ-61610588 to be delivered to the clinic significantly ahead of schedule.  

ImmuNext continues to identify and develop a pipeline of novel immunotherapies. For more information visit www.ImmuNext.com.

SOURCE: ImmuNext