PALO ALTO, CA, USA I October 16, 2014 I Cellular Biomedicine Group Inc. (NASDAQ: CBMG) (“CBMG” or the “Company”), a biomedicine firm engaged in the development of new treatments for degenerative and cancerous diseases, today announced the launch of a pre-clinical study of human adipose-derived mesenchymal progenitor cell (haMPC) therapy for Chronic Obstructive Pulmonary Disease (COPD). The study will evaluate the safety and efficacy of haMPCs to treat COPD.

Dr. Wei (William) Cao, Chief Executive Officer of Cellular Biomedicine Group, Inc., commented, “COPD poses a high economic and social burden on families and communities in China, due to the expense of prescription drugs and the impact on quality of life1, with many patients deteriorating to the point of being unable to work and a shortened life span. Over 32 million people in China2 suffer from COPD, so the need for innovative solutions is pressing as this disease represents a significant unmet medical need. We are very excited to further investigate the potential application of regenerative medicine technology in the field of respiratory disease”.

About COPD

Respiratory diseases account for 15% of deaths in China3. China currently has over 32 million patients suffering from COPD2. The major risk factors for COPD in China are tobacco smoking, biomass fuel use and genetic susceptibility1.

COPD refers to a group of diseases that block airflow to the lungs and make it difficult to breathe. The two most common conditions that make up COPD are chronic bronchitis and emphysema, which gradually destroys the smallest air passages (bronchioles) in the lungs. Currently the common treatments for COPD, such as use of steroids, inhalers and bronchodilator drugs, aim to control the symptoms and minimize further damage, but do not reverse the tissue damage.

About the Study

The pre-clinical study will be conducted by Shanghai First People’s Hospital, a leading teaching hospital affiliated with Shanghai Jiaotong University. Professor Zhou Xin, director of the hospital’s respiratory department and chairperson of Respiratory Diseases Division of Shanghai Medical Association, will lead the study as Principal Investigator. Prof. Zhou is also currently leading the Company’s pre-clinical study on adipose derived mesenchymal progenitor cell (haMPC) therapy for asthma.

Reference Material

   Journal of Thoracic Disease: Vol 5, No 4 (August 2013), Chronic obstructive pulmonary disease in China

   Based on estimates by World Health Organization (WHO) of 2.5% prevalence of COPD in China

   Respirology 2013, Asian Pacific Society of Respirology

About Cellular Biomedicine Group

Cellular Biomedicine Group, Inc. develops proprietary cell therapies for the treatment of certain degenerative diseases and cancers. Our developmental stem cell, progenitor cell, and immune cell projects are the result of research and development by scientists and doctors from China and the United States. Our flagship GMP facility, consisting of eight independent cell production lines, is designed, certified and managed according to U.S. standards. To learn more about CBMG, please visit: www.cellbiomedgroup.com.

SOURCE: Cellular Biomedicine Group