RESEARCH TRIANGLE PARK, NC, USA I September 4, 2014 I BioCryst Pharmaceuticals, Inc. (BCRX) today announced its participation in a consultation on potential Ebola therapies and vaccines hosted by the World Health Organization (WHO). The meeting is scheduled to take place September 4-5 in Geneva, Switzerland. According to the WHO, “The consultation has been convened to gather expertise about the most promising experimental therapies and vaccines and their role in containing the Ebola outbreak in west Africa.” The meeting agenda and other information are available at:

http://www.who.int/mediacentre/events/meetings/2014/ebola-interventions/en/

At the request of the WHO, BioCryst has furnished a one-page executive summary and a slide summary regarding BioCryst’s broad spectrum antiviral BCX4430 as a drug candidate for the treatment of Ebola Virus Disease and other hemorrhagic fever virus diseases. These documents summarize: nonclinical disease model and safety research results; anticipated timelines for filing an Investigational New Drug (IND) Application with the U.S. Food and Drug Administration to commence human safely studies of BCX4430; and projections for BCX4430 drug supply.

Electronic versions of the executive summary and presentation provided to the WHO by BioCryst are available on the corporate website at www.biocryst.com.

About the BSAV Program & BCX4430

The objective of BioCryst’s BSAV research program is to develop broad-spectrum parenteral and oral therapeutics for viruses that pose a threat to health and national security. The lead BSAV compound is BCX4430, an RNA dependent-RNA polymerase inhibitor that has demonstrated broad-spectrum activity against more than 20 RNA viruses in nine different families, including filoviruses, togaviruses, bunyaviruses, arenaviruses, paramyxoviruses, coronaviruses and flaviviruses. BioCryst is developing BCX4430 in collaboration with U.S. Government Agencies following the Animal Rule regulatory pathway.

About BioCryst Pharmaceuticals

BioCryst Pharmaceuticals designs, optimizes and develops novel small molecule drugs that block key enzymes involved in rare diseases. BioCryst currently has several ongoing development programs: oral inhibitors of plasma kallikrein for hereditary angioedema, including BCX4161 and several second generation compounds; peramivir, a viral neuraminidase inhibitor for the treatment of influenza, and BCX4430, a broad spectrum viral RNA polymerase inhibitor. For more information, please visit the Company’s website at www.BioCryst.com.

SOURCE: BioCryst Pharmaceuticals