Small Molecules

10 Jul 2018 VALBIOTIS Announces Positive Results from First Phase I/II Clinical Study of VAL-070 in Hypercholesterolemia
10 Jul 2018 Aeromics Initiates Phase 1 Clinical Trial of CNS Edema Inhibitor AER-271 In Healthy Human Volunteers
10 Jul 2018 Recursion Receives FDA Clearance of Investigational New Drug Application to Initiate First Clinical Trial of REC-994 in Cerebral Cavernous Malformation
10 Jul 2018 Achillion Initiates Phase I First-in-Human Study of ACH-5548, a Third Oral Small Molecule Inhibitor of Complement Factor D
10 Jul 2018 Assembly Biosciences Initiates Two Phase 2a Trials of ABI-H0731 for the Treatment of Hepatitis B Virus Infection
10 Jul 2018 Spero Announces Positive Interim Phase 1 SAD/MAD Results for SPR994
10 Jul 2018 BELLUS Health Initiates Phase 1 Clinical Study for its Chronic Cough Drug Candidate, BLU-5937
10 Jul 2018 XANTUS programme confirms low bleeding and low stroke rate with Xarelto® in 11,121 prospectively investigated patients with atrial fibrillation
10 Jul 2018 Results of Phase III (PIX306) Trial Evaluating Progression-Free Survival of PIXUVRI® (pixantrone) Combined with Rituximab in Patients with Aggressive B-cell Non-Hodgkin Lymphoma
06 Jul 2018 Orion has started a Phase III trial to develop a drug for ALS - The patient recruitment has begun
05 Jul 2018 Zynerba Pharmaceuticals Announces Top Line Results from ZYN001 THC-Prodrug Patch Phase 1 Study
05 Jul 2018 European Commission Approves Expanded Indication for Sprycel (dasatinib) to Include Treatment of Children with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase
04 Jul 2018 Abivax releases positive top line data from ABX464-005 phase 2a study in HIV infection
04 Jul 2018 FDA Approves ARISTADA INITIO™ for the Initiation of ARISTADA® for Schizophrenia
04 Jul 2018 First Volunteers Dosed in Phase I Clinical Trial of PBT434, Prana’s Lead Therapy for Parkinsonian Diseases
04 Jul 2018 Anavex Life Sciences Receives Approval To Initiate Phase 2b/3 Clinical Trial of ANAVEX®2-73 for the Treatment of Early Alzheimer’s Disease
04 Jul 2018 Forendo Pharma Initiates Phase I Study for Potential New, Targeted Treatment for Endometriosis
03 Jul 2018 NewLink Genetics Announces Positive Updated Phase 1 Data with Indoximod Plus Radio-Immunotherapy for Pediatric Patients with DIPG Presented at ISPNO 2018
03 Jul 2018 CHMP issues positive opinion to expand Jardiance®, Synjardy® and Glyxambi® labels to include positive effects on cardiovascular and renal outcomes
03 Jul 2018 Advicenne Confirms ADV7103’ Safety and Efficacy after 24 Months in the Phase III Extension Study
03 Jul 2018 Conatus Pharmaceuticals’ Pan-caspase Inhibitor Emricasan Improves Survival and Portal Hypertension in a Mouse Model of Cirrhosis
29 Jun 2018 XELJANZ® (tofacitinib citrate) Receives Marketing Authorisation in the European Union for Active Psoriatic Arthritis
29 Jun 2018 Puma Biotechnology Receives Positive CHMP Opinion Recommending Approval of NERLYNX® for Extended Adjuvant Treatment of HER2-Positive Early Stage Breast Cancer
29 Jun 2018 Vyxeos™ Receives Positive CHMP Opinion for Treatment of Certain Types of High-Risk Acute Myeloid Leukaemia
29 Jun 2018 FDA Lifts Clinical Hold so MYC Inhibitor APTO-253 Can Return to Phase 1b Trial In Patients With Hematologic Cancers

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